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laboras test boxes  (Metris Therapeutics)

 
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    Structured Review

    Metris Therapeutics laboras test boxes
    Overview of experiments and mice used for the respective experiments.
    Laboras Test Boxes, supplied by Metris Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/laboras+test+boxes/laboras+test+boxes/pmc11532339-43-5-29
    Average 90 stars, based on 1 article reviews
    laboras test boxes - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "The search for non-evoked markers of pain in the GTN mouse model of migraine"

    Article Title: The search for non-evoked markers of pain in the GTN mouse model of migraine

    Journal: Scientific Reports

    doi: 10.1038/s41598-024-78332-3

    Overview of experiments and mice used for the respective experiments.
    Figure Legend Snippet: Overview of experiments and mice used for the respective experiments.

    Techniques Used: Biomarker Discovery

    Schematic overview of experimental protocols and setup for each experiment. ( A ) Graphic illustration of timeline and study design for experiment 1–3. ( B ) Picture of LABORAS test cages. ( C ) Picture of burrowing tube in test cage. NB. Pictures do not represent the experimental light conditions. Created with BioRender.com.
    Figure Legend Snippet: Schematic overview of experimental protocols and setup for each experiment. ( A ) Graphic illustration of timeline and study design for experiment 1–3. ( B ) Picture of LABORAS test cages. ( C ) Picture of burrowing tube in test cage. NB. Pictures do not represent the experimental light conditions. Created with BioRender.com.

    Techniques Used:

    Data summary from Experiment 1 and 2. A) Von Frey test was performed before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 16/group, individual values and mean ± SEM. B-D) 4 h LABORAS data obtained from same mice as in A on days 1, 5, 7, and 9 immediately after GTN injection. No effect of GTN, but increased activity when testing during the dark phase (day 5), day effect p < 0.0001, Two-way repeated ANOVA. E-F) Von Frey data days 1–9 before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 12/group, mean ± SEM. G-H) Locomotion and distance traveled on day 11 with a 60 min delay of LABORAS initiation after GTN injection. Same mice as in E-F, students t-test.
    Figure Legend Snippet: Data summary from Experiment 1 and 2. A) Von Frey test was performed before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 16/group, individual values and mean ± SEM. B-D) 4 h LABORAS data obtained from same mice as in A on days 1, 5, 7, and 9 immediately after GTN injection. No effect of GTN, but increased activity when testing during the dark phase (day 5), day effect p < 0.0001, Two-way repeated ANOVA. E-F) Von Frey data days 1–9 before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 12/group, mean ± SEM. G-H) Locomotion and distance traveled on day 11 with a 60 min delay of LABORAS initiation after GTN injection. Same mice as in E-F, students t-test.

    Techniques Used: Injection, Comparison, Activity Assay

    Related Articles

    Software:

    Article Title: The search for non-evoked markers of pain in the GTN mouse model of migraine
    Article Snippet: .. The LABORAS setup consisted of LABORAS test boxes resembling home cages (22 × 16 × 14 cm), situated on the LABORAS platforms connected to a computer and LABORAS software-v2.6.9 (Metris B.V, The Netherlands). ..



    Similar Products

    laboras test boxes  (Metris Therapeutics)
    90
    Metris Therapeutics laboras test boxes
    Overview of experiments and mice used for the respective experiments.
    Laboras Test Boxes, supplied by Metris Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/laboras+test+boxes/laboras+test+boxes/pmc11532339-43-5-29
    Average 90 stars, based on 1 article reviews
    laboras test boxes - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Overview of experiments and mice used for the respective experiments.

    Journal: Scientific Reports

    Article Title: The search for non-evoked markers of pain in the GTN mouse model of migraine

    doi: 10.1038/s41598-024-78332-3

    Figure Lengend Snippet: Overview of experiments and mice used for the respective experiments.

    Article Snippet: The LABORAS setup consisted of LABORAS test boxes resembling home cages (22 × 16 × 14 cm), situated on the LABORAS platforms connected to a computer and LABORAS software-v2.6.9 (Metris B.V, The Netherlands).

    Techniques: Biomarker Discovery

    Schematic overview of experimental protocols and setup for each experiment. ( A ) Graphic illustration of timeline and study design for experiment 1–3. ( B ) Picture of LABORAS test cages. ( C ) Picture of burrowing tube in test cage. NB. Pictures do not represent the experimental light conditions. Created with BioRender.com.

    Journal: Scientific Reports

    Article Title: The search for non-evoked markers of pain in the GTN mouse model of migraine

    doi: 10.1038/s41598-024-78332-3

    Figure Lengend Snippet: Schematic overview of experimental protocols and setup for each experiment. ( A ) Graphic illustration of timeline and study design for experiment 1–3. ( B ) Picture of LABORAS test cages. ( C ) Picture of burrowing tube in test cage. NB. Pictures do not represent the experimental light conditions. Created with BioRender.com.

    Article Snippet: The LABORAS setup consisted of LABORAS test boxes resembling home cages (22 × 16 × 14 cm), situated on the LABORAS platforms connected to a computer and LABORAS software-v2.6.9 (Metris B.V, The Netherlands).

    Techniques:

    Data summary from Experiment 1 and 2. A) Von Frey test was performed before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 16/group, individual values and mean ± SEM. B-D) 4 h LABORAS data obtained from same mice as in A on days 1, 5, 7, and 9 immediately after GTN injection. No effect of GTN, but increased activity when testing during the dark phase (day 5), day effect p < 0.0001, Two-way repeated ANOVA. E-F) Von Frey data days 1–9 before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 12/group, mean ± SEM. G-H) Locomotion and distance traveled on day 11 with a 60 min delay of LABORAS initiation after GTN injection. Same mice as in E-F, students t-test.

    Journal: Scientific Reports

    Article Title: The search for non-evoked markers of pain in the GTN mouse model of migraine

    doi: 10.1038/s41598-024-78332-3

    Figure Lengend Snippet: Data summary from Experiment 1 and 2. A) Von Frey test was performed before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 16/group, individual values and mean ± SEM. B-D) 4 h LABORAS data obtained from same mice as in A on days 1, 5, 7, and 9 immediately after GTN injection. No effect of GTN, but increased activity when testing during the dark phase (day 5), day effect p < 0.0001, Two-way repeated ANOVA. E-F) Von Frey data days 1–9 before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 12/group, mean ± SEM. G-H) Locomotion and distance traveled on day 11 with a 60 min delay of LABORAS initiation after GTN injection. Same mice as in E-F, students t-test.

    Article Snippet: The LABORAS setup consisted of LABORAS test boxes resembling home cages (22 × 16 × 14 cm), situated on the LABORAS platforms connected to a computer and LABORAS software-v2.6.9 (Metris B.V, The Netherlands).

    Techniques: Injection, Comparison, Activity Assay